Director, Center for Developmental Therapeutics; Charles E. and Emma H. Morrison Professor of Chemistry; Professor of Molecular Biosciences; Weinberg College of Arts and Sciences; Director, Chemistry of Life Processes Institute; Director, Quantitative Bioelemental Imaging Center (QBIC); Senior Advisor to the Director of Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Thomas V. O'Halloran, Ph.D., directs interdisciplinary research programming at the interfaces of cell and molecular and cell biology, nanotechnology and bioinorganic chemistry. In his role of the Director of the Chemistry of Life Processes Institute, Dr. O'Halloran brings together teams of researchers from the fields of chemistry, biology, physics, engineering, medicine, proteomics, nanobiotechnology, molecular therapeutics, and biological molecular imaging with the mission of developing new insights and engineering solutions to pressing biomedical problems. He also serves as the Associate Director for the Basic Sciences Research Division of the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. He is also the Morrison Professor in the Department of Chemistry and in the Department of Molecular Biosciences at Northwestern and has founded several start-up companies in the biotech arena.
Dr. O'Halloran's research interests center on the assembly and characterization of novel agents which alter the regulatory biology of transition metal receptors involved in signaling and trafficking pathways. This work provided early insights into molecular regulatory mechanisms and has led to the discovery of new classes of soluble metal receptors: metalloregulatory and metallochaperone proteins. Most recently, he has discovered nanoscale processes for targeted delivery of multifunctional therapeutic agents based on the arsenic and platinum classes of anticancer agents for treatment of hematological cancer and solid tumors.
Professor O’Halloran received his B.S. and M.A. degrees in Chemistry from the University of Missouri, and a Ph.D. in 1985 from Columbia University. He joined the faculty of Northwestern University in 1986 after a National Research Service Award (NRSA) Postdoctoral Fellowship at Massachusetts Institute of Technology.
Office: Silverman Hall 4611
t-ohalloran [at] northwestern [dot] edu